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Matrix metalloproteinase 3 and 9 gene promoter polymorphisms: joint action of two loci as a risk factor for coronary artery complicated plaques Perttu J. Pöllänen, Terho Lehtimäki, Jussi Mikkelsson, Erkki Ilveskoski, Tarja Kunnas, Markus Perola, Antti Penttilä, Kari M. Mattila, Seppo T. Nikkari, Kirsi Syrjäkoski, Pekka J. Karhunen Atherosclerosis Volume 180, Issue 1, Pages (May 2005) DOI: /j.atherosclerosis Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions
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Fig. 1 Significant associations between mean per cent areas of complicated lesions (largest lesion in LAD, LCX or RCA) and combined matrix metalloproteinase MMP3 and MMP9 high and low promoter activity genotypes. Square root transformation. *One-way ANOVA, p-value adjusted for age, BMI, hypertension (yes/no), diabetes (yes/no), smoking (yes/no) and alcohol use <60g/d/≥60g/d. Atherosclerosis , 73-78DOI: ( /j.atherosclerosis ) Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions
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